徐志强,博士,副教授,硕士生导师
地址:湖北省武汉市东湖新技术开发区光谷一路206号,59白菜网
邮编:430205
Email:19070201@wit.edu.cn
教育背景
2014/09-2019/06,华中师范大学化学学院,博士
2010/09-2014/06,59白菜网,学士
工作简历
2023/12-至今,59论坛白菜专区,副教授
2021/07 -2022/07,香港城市大学,访问学者
2019/07 -2023/12,59论坛白菜专区,讲师
科研项目
1. 国家自然科学基金青年基金项目,“同时双色监控线粒体和溶酶体相互作用荧光探针的构建及应用研究”,24万元,主持
2. 59论坛白菜专区科学基金,5万元,主持
3. 国家自然科学基金面上项目,“谷胱甘肽和巯基氨基酸总量时空同步检测荧光探针的开发与应用”,64万元,参与
研究领域
化员工物学:有机合成;荧光传感、分子探针与生物成像及其生物医学应用
药物化学:药物递送系统与肿瘤靶向治疗,光学治疗
代表性论文:
1. Xu, Z.; Luo, Y.; Yang, X.; Ren, Y.; Liu, G.; Zhang, Zhang, M.-X. Synthesis and properties of D-π-A triphenylamine derivatives with solvatochromism and bioimaging application. J. Photochem. Photobio. A Chem. 2023, 444, 115002.
2. Zhang, M.-X.; Yang, X.; Tan, F.; Zhang, H.; Zeng, G.; Xu, Z.*; Liu, S. H. Synthesis, structure and mechanofluorochromic properties of phenothiazine-S-oxide and phenothiazine-S,S-dioxide derivatives. Spectrochim. Acta. A Mol. Biomol. Spectrosc. 2023, 292, 122427.
3. Zhang, M.-X.; Yang, X.; Tan, F. Ou, X.; Zeng, G.; Chen, D.; Xu, Z.*; Liu, S. H. Design, synthesis and properties of twisted D-A-D’ arylamine derivatives with solvatochromism. Dyes Pigments 2022, 204, 110420.
4. Xu, Z.; Luo, Y.; Hong, Y.; Liu, Z.; Zhang, M.-X.; Gu, S.-X.; Yin, J. A naphthimide-based ratiometric fluorescent probe for selective and visual detection of phosgene in solution and the gas phase. Spectrochim. Acta. A Mol. Biomol. Spectrosc. 2022, 269, 120789.
5. Xu, Z.; Yang, X.; Liu, Z. Zhang, M.-X. A 1,8-naphthimide-based fluorescent probe for detection of formaldehyde in gaseous and application in living cells. J. Photochem. Photobio. A Chem. 2022, 426, 113731.
6. Yang, L; Liu, G.; Chen, Q.; Wan, Y.; Liu, Z.; Zhang, J.; Huang, C.; Xu, Z.; Li, S.; Lee, C.-S.; Zhang, L.; Sun, H. An activatable NIR probe for the detection and elimination of senescent cells. Anal. Chem. 2022, 94, 5425-5431.
7. Zhang, M.-X.; Yang, X.; Xu, Z.*; Yin, J.; Liu,S. H. Light- and heat-controlled formation of Osmanaphthalenes and Osmanaphthalynes. Chin. J. Chem. 2022, 40, 2853-2860.
8. Zhang, M.-X.; Jin, X.; Yang, X.; Xu, Z.*; Liu, S. H. Synthesis and properties of 3-fold symmetrical hexabenzocoronene-bridged trinuclear alkynylgold(I) complexes. J. Coord. Chem. 2021, 74, 1765-1780.
9. Xu, Z.; Huang, X.; Zhang, M.-X.; Chen, W.; Liu, S. H.; Tan, Y.; Yin, J. Tissue-imaging of glutathione-specific naphthalimide-cyanine dye with two-photon and near-infrared manners. Anal. Chem. 2019, 91, 11343-11348.
10. Xu, Z.; Zhang, M.-X.; Xu, Y.; Liu, S. H.; Zeng, L.; Chen, H.; Yin, J. The visualization of lysosomal and mitochondrial glutathione via near-infrared fluorophore and in vivo imaging application. Sens. Actuators B: Chem. 2019, 290, 676-683.
11. Xu, Z.; Zhang, M.-X.; Li, G. Chen, X.; Liu, S. H.; Chen, H.*; Yin, J.* Naphthalimide-sulfonamide fused dansyl-sulfonamide fluorescent probe for tracking glutathione of lysosome with a dual-emission manner. Dyes pigments 2019, 171, 107685.
12. Xu, Z.; Huang, X.; Han, X. Wu, D.; Zhang, B.; Tan, Y.; Cao, M.; Liu, S. H.; Yin, J.; Yoon, J. A visible and near-infrared, dual-channel fluorescence-on probe for selectively tracking mitochondrial glutathione. Chem 2018, 4, 1609-1628.
13. Xu, Z.; Chen, J.; Hu, L.-L.*; Tan, Y.*; Liu, S. H.; Yin, J.* Recent advances in formaldehyde-responsive fluorescent probes. Chin. Chem. Lett. 2017, 28, 1935-1942.
14. Xu, Z.; Ge, H.; Han, X.; Liu, S. H.; Meng, X.-G.*; Yin, J.* Self-recognition behavior of novel frameworks containing both urea and carboxylate anion motifs. Tetrahedron 2017, 73, 6386-6391.
获奖情况
1. 第九届中国国际“互联网+”老员工创新创业大赛全国三等奖,2023年,指导老师
2. 第九届“互联网+”老员工创新创业大赛湖北省金奖,2023年,指导老师
3. 全国老员工生命科学竞赛一等奖,2023年,指导老师
4. “东富龙-国药工程杯”第十一届全国老员工制药工程设计竞赛二等奖,2023年,指导老师
5. 全国老员工生命科学竞赛一等奖,2022年,指导老师
6. 湖北省第十二届“挑战杯”老员工创业计划竞赛二等奖,2022年,指导老师
7. 59论坛白菜专区第八届“互联网+”老员工创新创业大赛金奖,2022年,指导老师
8. 59论坛白菜专区第十五届“挑战杯”老员工竞赛三等奖,2021年,指导老师
9. 2021年59论坛白菜专区优秀班主任
10. 2020年59论坛白菜专区“先进个人”荣誉称号(抗疫)。
欢迎各位有志之士报考硕士研究生!